Laminaria sp و Sargassum. sp التأثير الضد بكتيري لمستخلصات طحلبي
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2024-07-01
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Summary: The current study included the extraction and identification of some active chemical compounds from the brown alga Sargassum sp. and brown algae Laminaria sp. and studying the effect of the inhibitory activity of extracts of these two algae against some types of pathogenic bacteria that included Pseudomonas aeruginosa, Escherichia coli, Salmonella sp. , Bacillus cereus , Staphylococcus aureus and Streptococcus mutans , where the active chemical compounds were extracted from these two algae using different solvents (cold water, methanol alcohol, and ethanol) with qualitative detections of secondary metabolites of the aqueous extracts of both algae, which indicated the presence of chemically active compounds such as alkaloids, phenols, flavonoids, glycosides, terpenoids, taninns, saponins , carotenoids , steroids and amino acid . The cytotoxicity of the aqueous extract of both algae against human red blood cells was tested, as no toxicity of the algal extract was shown throughout the experiment. The active chemical compounds, which have the highest percentage among the other compounds, were identified using Gas chromatography mass spectrometry (Gc-mass) technique of the methanolic extract of Sargassum sp. These compounds were Oleic acid, n-Hexadecanoic acid and Tetradecanoic acid.